Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETDB1 | Q15047 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660658 | 0.87 | SETDB1 (0.39) | SETDB1SMN1; SMN2MAPTLMNABRD9 | |
| SCHEMBL8675983 | 0.84 | SETDB1 (0.38) | SETDB1SMN1; SMN2LMNABRD9BRD7 | |
| SCHEMBL8663188 | 0.81 | ALDH1A1 (0.42) | SETDB1KMT2ASMN1; SMN2TP53LMNA | |
| SCHEMBL8155272 | 0.81 | NPC1 (0.34) | SETDB1KMT2ASMN1; SMN2LMNABRD9 | |
| SCHEMBL8499784 | 0.71 | ALDH1A1 (0.36) | KMT2ALMNABRD9MEN1 | |
| SCHEMBL8670561 | 0.69 | DDR1 (0.35) | SETDB1NPSR1SMN1; SMN2LMNABRD9 | |
| SCHEMBL23712860 | 0.68 | P2RX7 (0.35) | KMT2ASMN1; SMN2MAPTBRD9MEN1 | |
| SCHEMBL12641402 | 0.67 | KMT2A (0.40) | SETDB1KMT2ANPSR1 | |
| SCHEMBL8590523 | 0.65 | KDM4E (0.47) | KMT2AMAPTLMNAMEN1GAA | |
| SCHEMBL8593864 | 0.63 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2TP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874831-A1 | PROCESSES AND COMPOUNDS FOR PREPARING CYCLIC UREA FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997019935-A1 | PROCESSES AND COMPOUNDS FOR PREPARING CYCLIC UREA FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-06-05 | — | — | WO | disclosed |