Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETDB1 | Q15047 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664609 | 0.87 | SETDB1 (0.37) | SETDB1BRD9SMN1; SMN2MAPTLMNA | |
| SCHEMBL8675983 | 0.86 | SETDB1 (0.38) | SETDB1BRD9TSHRSMN1; SMN2LMNA | |
| SCHEMBL8155272 | 0.82 | NPC1 (0.34) | SETDB1BRD9SMN1; SMN2LMNA | |
| SCHEMBL8670561 | 0.80 | DDR1 (0.35) | SETDB1BRD9GABRG2GABRB3GABRA5 | |
| SCHEMBL8664792 | 0.80 | SETDB1 (0.42) | SETDB1TLR8SMN1; SMN2MAPTLMNA | |
| SCHEMBL6600347 | 0.72 | MALT1 (0.35) | SETDB1BRD9TSHRSMN1; SMN2LMNA | |
| SCHEMBL8499784 | 0.70 | ALDH1A1 (0.36) | BRD9TSHRLMNAHTT | |
| SCHEMBL8663188 | 0.69 | ALDH1A1 (0.42) | SETDB1BRD9SMN1; SMN2LMNAHTT | |
| SCHEMBL8664376 | 0.69 | SMN1; SMN2 (0.33) | SETDB1BRD9SMN1; SMN2MAPTLMNA | |
| SCHEMBL6603431 | 0.67 | HCAR1 (0.48) | TSHRSMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874831-A1 | PROCESSES AND COMPOUNDS FOR PREPARING CYCLIC UREA FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997019935-A1 | PROCESSES AND COMPOUNDS FOR PREPARING CYCLIC UREA FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-06-05 | — | — | WO | disclosed |