SCHEMBL8664446

SCHEMBL8664446

CC(OC(N)=O)S(=O)(=O)c1ccc(F)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 3/20 0.44
PRSS1 P07477 3/20 0.44
PRSS2 P07478 3/20 0.44
PRSS3 P35030 3/20 0.44
MMP1 P03956 2/20 0.39
MMP2 P08253 2/20 0.39
MMP9 P14780 2/20 0.39
MMP13 P45452 2/20 0.39
MMP3 P08254 1/20 0.39
MMP7 P09237 1/20 0.39
CA1 P00915 6/20 0.39
CA2 P00918 6/20 0.39
CA9 Q16790 3/20 0.39
CA12 O43570 2/20 0.39
CA7 P43166 2/20 0.39
CA14 Q9ULX7 1/20 0.39
PSEN1 P49768 2/20 0.39
PSEN2 P49810 2/20 0.39
APH1B Q8WW43 2/20 0.39
NCSTN Q92542 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL528908 0.85 ALDH1A1 (0.46) F2PRSS1PRSS2PRSS3MMP1
SCHEMBL8662610 0.83 NPC1 (0.45) F2PRSS1PRSS2PRSS3MMP1
SCHEMBL787248 0.83 TSHR (0.44) MMP1MMP13MMP7CA1CA2
SCHEMBL29323716 0.80 MMP1 (0.37) F2PRSS1PRSS2PRSS3MMP1
SCHEMBL27874923 0.75 F2 (0.47) F2PRSS1PRSS2PRSS3MMP1
SCHEMBL1368959 0.72 CA1 (0.48) MMP1MMP2MMP9MMP13MMP3
SCHEMBL28649908 0.72 ALDH1A1 (0.41) ALDH1A1
SCHEMBL9090928 0.72 ALDH1A1 (0.41) ALDH1A1
SCHEMBL16232170 0.72 MMP2 (0.50) MMP1MMP2MMP9MMP13MMP3
SCHEMBL18007730 0.71 F2 (0.50) F2PRSS1PRSS2PRSS3MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714889-B1 SULFONYLSEMICARBAZIDE DERIVATIVE AND COMPOSITION FOR KEEPING CUT FLOWER FRESHNESS MEIJI SEIKA KAISHA (JP) 1998-11-25 EP disclosed
US-5723407-A Sulfonylsemicarbazide derivatives and preservative composition for preserving the freshness of flower of cut flowers MEIJI SEIKA KAISHA, LTD. (JP) 1998-03-03 US disclosed
EP-0714889-A1 SULFONYLSEMICARBAZIDE DERIVATIVE AND COMPOSITION FOR KEEPING CUT FLOWER FRESHNESS MEIJI SEIKA KAISHA LTD. (JP) 1996-06-05 EP disclosed