SCHEMBL528908

SCHEMBL528908

Cc1ccc(S(=O)(=O)C(C)OC(N)=O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA12 O43570 2/20 0.46
CA9 Q16790 2/20 0.46
F2 P00734 3/20 0.43
PRSS1 P07477 3/20 0.43
PRSS2 P07478 3/20 0.43
PRSS3 P35030 3/20 0.43
CA3 P07451 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
GAA P10253 1/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
PTPN7 P35236 1/20 0.39
GBA1 P04062 1/20 0.39
MMP1 P03956 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8662610 0.85 NPC1 (0.45) ALDH1A1CA1CA2CA12CA9
SCHEMBL8664446 0.85 F2 (0.44) ALDH1A1CA1CA2CA12CA9
SCHEMBL787248 0.84 TSHR (0.44) ALDH1A1CA1CA2CA12CA9
SCHEMBL27584031 0.84 CA1 (0.43) ALDH1A1CA1CA2CA12CA9
SCHEMBL5931092 0.80 ALDH1A1 (0.44) ALDH1A1CA1CA2CA12CA9
SCHEMBL571764 0.77 ALDH1A1 (0.50) ALDH1A1CA1CA2CA12CA9
SCHEMBL3442045 0.77 CA1 (0.56) ALDH1A1CA1CA2CA12CA9
SCHEMBL28271705 0.76 ALDH1A1 (0.44) ALDH1A1CA1CA2CA12CA9
SCHEMBL20521612 0.76 GAA (0.48) ALDH1A1CA1CA2CA12CA9
SCHEMBL24334208 0.76 ALDH1A1 (0.54) ALDH1A1CA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0569294-B1 Use of an arylsulfonylurethane as strengthening resin in nitrocellulose nail lacquers, arylsulfonylurethanes and nitrocellulose nail lacquers POUDRES & EXPLOSIFS STE NALE (FR) 1996-07-17 EP claimed
WO-2024130217-A1 STAPLED PEPTIDES AND METHODS THEREOF FOG PHARMACEUTICALS, INC. (US) 2024-06-20 WO disclosed
WO-2023168066-A9 OXIME-BASED HOT MELT ADHESIVES FOR REWORK, REPAIR AND RECYCLE CONAGEN INC. (US) 2024-06-20 WO disclosed
WO-2024130218-A1 STAPLED PEPTIDES AND METHODS THEREOF FOG PHARMACEUTICALS, INC. (US) 2024-06-20 WO disclosed
EP-4355350-A1 STAPLED PEPTIDES AND METHODS THEREOF Fog Pharmaceuticals, Inc. (US) 2024-04-24 EP disclosed
WO-2023168066-A1 OXIME-BASED HOT MELT ADHESIVES FOR REWORK, REPAIR AND RECYCLE CONAGEN INC. (US) 2023-09-07 WO disclosed
WO-2022261257-A1 STAPLED PEPTIDES AND METHODS THEREOF FOG PHARMACEUTICALS, INC. (US) 2022-12-15 WO disclosed
WO-2021146553-A1 MACROMOLECULAR PRODRUGS FOR LIGHT-EMITTING DIODES AND USES THEREOF CHILDREN'S MEDICAL CENTER CORPORATION (US) 2021-07-22 WO disclosed
US-20200223884-A1 3,3 DISUBSTITUTED 19-NOR PREGNANE COMPOUNDS, COMPOSITIONS, AND USES THEREOF SAGE THERAPEUTICS INC (US) 2020-07-16 US disclosed
US-20190350931-A1 COMBINATION THERAPY GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2019-11-21 US disclosed
EP-2598170-A2 DRUG-LIGAND CONJUGATES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO Smartcells, Inc. (US) 2013-06-05 EP disclosed
WO-2012015681-A2 DRUG-LIGAND CONJUGATES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO SMARTCELLS, INC. (US) 2012-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190350931-A1 COMBINATION THERAPY PRMT1, PRMT6, PRMT3 ALDH1A1 3876/4885CA1 2138/4885CA2 1907/4885
US-20200223884-A1 3,3 DISUBSTITUTED 19-NOR PREGNANE COMPOUNDS, COMPOSITIONS, AND USES THEREOF HSD3B1, HSD3B2, CYP11B1 ALDH1A1 495/4885CA1 2056/4885CA2 4439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.