SCHEMBL8664544

SCHEMBL8664544

C=COC(=O)C=Cc1ccc(OC)c(OC)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.65
ALDH1A1 P00352 4/20 0.65
SMN1; SMN2 Q16637 3/20 0.65
HPGD P15428 1/20 0.65
ALOX15 P16050 1/20 0.65
MAPK1 P28482 1/20 0.65
HSD17B10 Q99714 1/20 0.65
NFE2L2 Q16236 1/20 0.63
KMT2A Q03164 5/20 0.61
ABCG2 Q9UNQ0 2/20 0.61
MEN1 O00255 1/20 0.61
FDPS P14324 2/20 0.59
EPHX2 P34913 1/20 0.56
TNFRSF1A P19438 1/20 0.56
NPC1 O15118 1/20 0.55
MAPT P10636 1/20 0.55
RAB9A P51151 1/20 0.55
TTR P02766 1/20 0.55
JUN P05412 1/20 0.55
NFKB1 P19838 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28222071 0.90 JUN (0.71) KDM4EALDH1A1SMN1; SMN2HPGDALOX15
SCHEMBL16816896 0.88 EPHX2 (0.74) KDM4EALDH1A1HPGDALOX15MAPK1
SCHEMBL28518772 0.88 EPHX2 (0.74) KDM4EALDH1A1HPGDALOX15MAPK1
Methyl Cis-3,4-Dimethoxycinnamate SCHEMBL2411956 0.84 FDPS (0.80) KDM4EALDH1A1SMN1; SMN2HPGDALOX15
Methyl Cis-3,4-Dimethoxycinnamate SCHEMBL2411955 0.84 FDPS (0.80) KDM4EALDH1A1SMN1; SMN2HPGDALOX15
SCHEMBL12538642 0.81 SMN1; SMN2 (0.69) KDM4EALDH1A1SMN1; SMN2HPGDALOX15
SCHEMBL29428460 0.81 KDM4E (0.69) KDM4EALDH1A1SMN1; SMN2HPGDALOX15
SCHEMBL10929433 0.81 KDM4E (0.69) KDM4EALDH1A1SMN1; SMN2HPGDALOX15
SCHEMBL2743877 0.80 NFKB1 (0.79) KDM4EALDH1A1SMN1; SMN2HPGDALOX15
SCHEMBL30493821 0.80 NFKB1 (0.79) KDM4EALDH1A1SMN1; SMN2HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0883016-A1 Method for producing phase retarder films SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-12-09 EP disclosed