Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664577 | 0.91 | ALDH1A1 (0.45) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL1985195 | 0.69 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL18093460 | 0.65 | ALDH1A1 (0.81) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL26268285 | 0.65 | ALDH1A1 (0.40) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL8735574 | 0.64 | ADRB2 (0.61) | ALDH1A1KDM4EKMT2AHSD17B10HPGD | |
| SCHEMBL7592012 | 0.62 | TSHR (0.44) | ALDH1A1KDM4EKMT2AMAPTTDP1 | |
| SCHEMBL22724577 | 0.60 | FPR2 (0.41) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL21733835 | 0.60 | MAPT (0.37) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL25273498 | 0.59 | KDM4E (0.64) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL30488146 | 0.59 | KDM4E (0.64) | ALDH1A1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933335-A | Quinolones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1990-06-12 | — | — | US | disclosed |