Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CRHBP | P24387 | 2/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831658 | 0.88 | PTPRB (0.47) | CTSSCTSKALDH1A1CRHBPCRHR2 | |
| SCHEMBL8222967 | 0.85 | CTSK (0.50) | CTSSCTSKSYKPOLBMEN1 | |
| SCHEMBL20777776 | 0.85 | CTSS (0.50) | CTSSCTSKSYKMAPT | |
| SCHEMBL266022 | 0.85 | CTSK (0.51) | CTSSCTSKSYKMEN1KMT2A | |
| SCHEMBL266021 | 0.85 | CTSK (0.51) | CTSSCTSKSYKMEN1KMT2A | |
| SCHEMBL118384 | 0.85 | CTSK (0.51) | CTSSCTSKSYKMEN1KMT2A | |
| SCHEMBL8122648 | 0.84 | ALDH1A1 (0.47) | CTSSCTSKALDH1A1SMN1; SMN2SYK | |
| SCHEMBL13300078 | 0.84 | LMNA (0.49) | CTSSCTSKALDH1A1CRHBPCRHR2 | |
| SCHEMBL6161127 | 0.84 | CTSS (0.49) | CTSSCTSKSYKMAPT | |
| SCHEMBL12028293 | 0.83 | CTSK (0.50) | CTSSCTSKSYKMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719251-B1 | BICYCLO (2.2.2) OCTANE DERIVATIVES CHOLECYSTOKININ AND/OR GASTRIN ANTAGONISTS | BLACK JAMES FOUNDATION (GB) | 1998-12-09 | — | — | EP | disclosed |
| US-5514683-A | LIGANDS FKOR CHOLECYSTOKININ OR GASTRIN RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 1996-05-07 | — | — | US | disclosed |