Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Benzidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 6/20 | 0.61 |
| ▸ | CA1 | P00915 | 5/20 | 0.61 |
| ▸ | CA12 | O43570 | 5/20 | 0.61 |
| ▸ | CA9 | Q16790 | 5/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | NT5E | P21589 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzidine SCHEMBL20957554 | 0.95 | CYP3A4 (0.58) | CYP3A4ALDH1A1TDP1TP53CA2 | |
| Benzidine SCHEMBL11377570 | 0.92 | CA2 (0.65) | CYP3A4ALDH1A1TDP1TP53CA2 | |
| Sulfuric Acid SCHEMBL28572498 | 0.91 | TSHR (0.68) | CYP3A4ALDH1A1TDP1TP53CA2 | |
| Sulfuric Acid SCHEMBL28270834 | 0.91 | TSHR (0.68) | CYP3A4ALDH1A1TDP1TP53CA2 | |
| Sulfuric Acid SCHEMBL147074 | 0.91 | TSHR (0.68) | CYP3A4ALDH1A1TDP1TP53CA2 | |
| Biphenyl-4-Amine SCHEMBL28526921 | 0.88 | CYP3A4 (0.68) | CYP3A4ALDH1A1TDP1TP53CA2 | |
| Sulfuric Acid SCHEMBL1599590 | 0.88 | TSHR (0.65) | CYP3A4ALDH1A1TDP1TP53CA2 | |
| Sulfuric Acid SCHEMBL28964013 | 0.88 | TSHR (0.65) | CYP3A4ALDH1A1TDP1TP53CA2 | |
| Sulfuric Acid SCHEMBL27972059 | 0.88 | TSHR (0.65) | CYP3A4ALDH1A1TDP1TP53CA2 | |
| Sulfuric Acid SCHEMBL28270642 | 0.88 | TSHR (0.65) | CYP3A4ALDH1A1TDP1TP53CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105973876-B | It is a kind of detect dopamine electrochemical luminescence sensor and its preparation and application | 国家纳米科学中心 | 2019-04-30 | — | — | CN | claimed |
| US-9717939-B2 | Fire extinguishing composition containing transition metal compound | XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD (CN) | 2017-08-01 | — | — | US | claimed |
| CN-106885871-A | A kind of assay method of complicated solution middle and high concentration sulfate radical | 北京有色金属研究总院 | 2017-06-23 | — | — | CN | claimed |
| CN-105973876-A | Electrochemiluminescence sensor for detecting dopamine, and production method and application thereof | 国家纳米科学中心 | 2016-09-28 | — | — | CN | claimed |
| US-20150190664-A1 | FIRE EXTINGUISHING COMPOSITION CONTAINING TRANSITION METAL COMPOUND | XI'AN J&R FIRE FIGHTING EQUIPMENT CO., LTD. (CN) | 2015-07-09 | — | — | US | claimed |
| EP-2799118-A1 | FIRE EXTINGUISHING COMPOSITION CONTAINING TRANSITION METAL COMPOUND | Xi'an J&R Fire Fighting Equipment Co., Ltd. (CN) | 2014-11-05 | — | — | EP | claimed |
| CN-103170083-A | Fire extinguishing composition containing transition metal compound | SHAANXI J & R FIRE FIGHTING CO | 2013-06-26 | — | — | CN | claimed |
| US-20250180952-A1 | PHOTOALIGNING MATERIALS | Rolic Technologies AG (CH) | 2025-06-05 | — | — | US | disclosed |
| EP-4493638-A1 | PHOTOALIGNING MATERIALS | Rolic Technologies AG (CH) | 2025-01-22 | — | — | EP | disclosed |
| CN-118846991-B | Process system and process method for continuously producing 4,4' -biphenol intermediate | 北京弗莱明科技有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-118871548-A | Photoalignment materials | 罗利克技术有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-118846991-A | Process system and process method for continuously producing 4,4' -biphenol intermediate | 北京弗莱明科技有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-118027412-A | Photo-alignment material | 罗利克技术有限公司 | 2024-05-14 | — | — | CN | disclosed |
| EP-2308827-A1 | Photocrosslinkable materials | Rolic AG (CH) | 2011-04-13 | — | — | EP | disclosed |
| EP-2305632-A1 | Photocrosslinkable materials | Rolic AG (CH) | 2011-04-06 | — | — | EP | disclosed |
| EP-2305631-A1 | Photocrosslinkable materials | Rolic AG (CH) | 2011-04-06 | — | — | EP | disclosed |
| US-20100266814-A1 | PHOTOALIGNMENT COMPOSITION | ROLIC AG (CH) | 2010-10-21 | — | — | US | disclosed |
| US-20100048849-A1 | PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP | ROLIC AG (CH) | 2010-02-25 | — | — | US | disclosed |
| US-20080293888-A1 | Photocrosslinkable Materials | ROLIC AG (CH) | 2008-11-27 | — | — | US | disclosed |
| US-6022307-A | ANGIOGENESIS INHIBITOR | AMERICAN CYANAMID COMPANY (US) | 2000-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048849-A1 | PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP | DDC, ALAD, DYNC1LI1 | CYP3A4 4068/4885ALDH1A1 97/4885TDP1 840/4885 |
| US-20080293888-A1 | Photocrosslinkable Materials | DDC, PARG, ALAD | CYP3A4 4202/4885ALDH1A1 313/4885TDP1 914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.