Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666837 | 0.82 | HTT (0.43) | ALDH1A1KDM4EHPGDHSD17B10FKBP1A | |
| SCHEMBL8668679 | 0.81 | MEN1 (0.43) | ALDH1A1GAAKMT2ATSHR | |
| Hydrochloric Acid SCHEMBL8672045 | 0.80 | MEN1 (0.42) | ALDH1A1GAAKMT2ATSHR | |
| SCHEMBL8672057 | 0.80 | GRM5 (0.39) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL8668250 | 0.75 | POLB (0.46) | KMT2APOLBHTTSMN1; SMN2ATM | |
| Hydrochloric Acid SCHEMBL8683994 | 0.73 | SMN1; SMN2 (0.38) | ALDH1A1HSD17B10TSHRPOLBSMN1; SMN2 | |
| SCHEMBL8666843 | 0.72 | MEN1 (0.38) | ALDH1A1GAAKMT2A | |
| SCHEMBL8669627 | 0.72 | KMT2A (0.40) | GAAKMT2ATSHR | |
| SCHEMBL8665662 | 0.71 | HDAC2 (0.40) | KDM4EHPGDGAAKMT2APOLB | |
| SCHEMBL8666356 | 0.70 | LMNA (0.41) | ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |