Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8672045 | 0.98 | MEN1 (0.42) | MEN1KMT2ACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL8669627 | 0.89 | KMT2A (0.40) | MEN1KMT2ACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL8666843 | 0.83 | MEN1 (0.38) | MEN1KMT2ACYP3A4CYP2C9KDM1A | |
| SCHEMBL8665746 | 0.81 | ALDH1A1 (0.40) | KMT2ATSHRALDH1A1GAA | |
| SCHEMBL8666356 | 0.80 | LMNA (0.41) | MEN1KMT2ACYP3A4CYP2C9LMNA | |
| SCHEMBL8683694 | 0.79 | KMT2A (0.41) | MEN1KMT2ACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL2804427 | 0.79 | CYP2D6 (0.45) | MEN1KMT2ACYP2C9CYP2D6LMNA | |
| SCHEMBL8666857 | 0.78 | KMT2A (0.38) | MEN1KMT2ACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL8871034 | 0.78 | KMT2A (0.38) | MEN1KMT2ACYP3A4CYP2C9CYP2D6 | |
| SCHEMBL8672057 | 0.77 | GRM5 (0.39) | MEN1KMT2ACYP3A4CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |