Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668534 | 0.84 | SMN1; SMN2 (0.46) | POLBATMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8668679 | 0.77 | MEN1 (0.43) | MEN1KMT2AL3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL8672045 | 0.76 | MEN1 (0.42) | MEN1KMT2AL3MBTL1NPSR1 | |
| SCHEMBL8665746 | 0.75 | ALDH1A1 (0.40) | POLBATMSMN1; SMN2KMT2AHTT | |
| SCHEMBL5325812 | 0.75 | POLB (0.63) | POLBTDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8672057 | 0.73 | GRM5 (0.39) | SMN1; SMN2MEN1KMT2AL3MBTL1HTT | |
| SCHEMBL8666843 | 0.68 | MEN1 (0.38) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL3330822 | 0.68 | POLB (0.63) | POLBSMN1; SMN2MEN1KMT2ANOTUM | |
| SCHEMBL3330829 | 0.68 | POLB (0.63) | POLBSMN1; SMN2MEN1KMT2ANOTUM | |
| SCHEMBL8669627 | 0.68 | KMT2A (0.40) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |