Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666854 | 0.82 | LMNA (0.37) | LMNATAAR1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8683686 | 0.81 | LMNA (0.38) | LMNAKMT2AALDH1A1L3MBTL1MEN1 | |
| SCHEMBL8668679 | 0.80 | MEN1 (0.43) | LMNAKMT2AALDH1A1L3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL8672045 | 0.79 | MEN1 (0.42) | LMNAKMT2AALDH1A1L3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL8683766 | 0.77 | REN (0.38) | LMNAKMT2AALDH1A1L3MBTL1MEN1 | |
| SCHEMBL8683956 | 0.77 | POLB (0.36) | LMNAKMT2AALDH1A1L3MBTL1MEN1 | |
| SCHEMBL8684040 | 0.75 | MEN1 (0.39) | LMNAKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL8686069 | 0.75 | RAB9A (0.38) | LMNAKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL8684409 | 0.74 | KAT6A (0.39) | LMNAALDH1A1 | |
| SCHEMBL8666843 | 0.74 | MEN1 (0.38) | KMT2AALDH1A1L3MBTL1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |