Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.46 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.43 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.43 |
| ▸ | NAE1 | Q13564 | 2/20 | 0.41 |
| ▸ | UBA3 | Q8TBC4 | 2/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.41 |
| ▸ | ATG7 | O95352 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL866868 | 1.00 | ADORA3 (0.46) | ADORA3ADORA2AADORA1METTL3METTL14 | |
| SCHEMBL866807 | 0.91 | ATG7 (0.41) | ADORA3NAE1UBA3SAE1ATG7 | |
| SCHEMBL867352 | 0.91 | ATG7 (0.41) | ADORA3NAE1UBA3SAE1ATG7 | |
| SCHEMBL10185764 | 0.91 | ATG7 (0.41) | ADORA3NAE1UBA3SAE1ATG7 | |
| SCHEMBL867142 | 0.90 | DNPH1 (0.44) | ADORA3NAE1UBA3SAE1ATG7 | |
| SCHEMBL867139 | 0.90 | DNPH1 (0.44) | ADORA3NAE1UBA3SAE1ATG7 | |
| SCHEMBL866212 | 0.85 | AURKA (0.42) | ADORA3ADORA2AADORA1NAE1UBA3 | |
| SCHEMBL865269 | 0.85 | AURKA (0.42) | ADORA3ADORA2AADORA1NAE1UBA3 | |
| SCHEMBL866315 | 0.81 | ATG7 (0.43) | ADORA1NAE1UBA3SAE1ATG7 | |
| SCHEMBL867742 | 0.81 | ATG7 (0.43) | ADORA1NAE1UBA3SAE1ATG7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077814-A1 | SULFONAMIDE, SULFAMATE, AND SULFAMOTHIOATE DERIVATIVES | WANG ZHONG (US) | 2012-03-29 | — | — | US | claimed |
| US-20120077814-A1 | SULFONAMIDE, SULFAMATE, AND SULFAMOTHIOATE DERIVATIVES | WANG ZHONG (US) | 2012-03-29 | — | — | US | disclosed |
| US-20120077814-A1 | SULFONAMIDE, SULFAMATE, AND SULFAMOTHIOATE DERIVATIVES | WANG ZHONG (US) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077814-A1 | SULFONAMIDE, SULFAMATE, AND SULFAMOTHIOATE DERIVATIVES | NEDD8, NAE1, UBA3 | ADORA3 3756/4885ADORA2A 3691/4885ADORA1 3112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.