Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 8/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 8/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20652825 | 0.78 | LMNA (0.71) | LMNATDP1NR1I2CYP1A2CYP3A4 | |
| SCHEMBL11332669 | 0.77 | ALDH1A1 (0.50) | KDM4EEPHX1 | |
| SCHEMBL11764786 | 0.75 | ALDH1A1 (0.43) | CYP1A2KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL7462682 | 0.73 | HTR3E (0.48) | TDP1MAPTHSD17B1HSD17B2SMN1; SMN2 | |
| SCHEMBL18773869 | 0.71 | MEN1 (0.56) | LMNATDP1NR1I2CYP1A2CYP3A4 | |
| SCHEMBL22852718 | 0.71 | TERT (0.47) | LMNATDP1HSD17B1HSD17B2SMN1; SMN2 | |
| SCHEMBL21870620 | 0.71 | HSD17B1 (0.54) | LMNATDP1NR1I2CYP1A2CYP3A4 | |
| SCHEMBL12048748 | 0.71 | TDP1 (0.54) | LMNATDP1NR1I2CYP1A2CYP3A4 | |
| SCHEMBL7458789 | 0.70 | MAPT (0.45) | MAPTHSD17B1HSD17B2SMN1; SMN2 | |
| SCHEMBL2088201 | 0.70 | HSD17B1 (0.57) | LMNATDP1NR1I2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61018716-A | — | — | None | — | — | JP | disclosed |
| JP-61257920-A | — | — | None | — | — | JP | disclosed |
| US-5810944-A | Cleanser for surgical instruments | CHEMISCHE FABRIK DR. WEIGERT (GMBH & CO.) (DE) | 1998-09-22 | — | — | US | disclosed |
| EP-0309624-B1 | COMPOSITION FOR ENHANCING PERCUTANEOUS ADMINISTRATION OF MEDICINE | NITTO DENKO CORPORATION (JP) | 1992-03-11 | — | — | EP | disclosed |
| US-5059628-A | Proline or prolinol ester to enhance absorption | NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1991-10-22 | — | — | US | disclosed |
| EP-0309624-A1 | Composition for enhancing percutaneous administration of medicine | NITTO DENKO CORPORATION (JP) | 1989-04-05 | — | — | EP | disclosed |
| JP-S61257920-A | ANTIMYCOTIC GELATINOUS AGENT FOR EXTERNAL USE | SATO SEIYAKU KK | 1986-11-15 | — | — | JP | disclosed |
| JP-S6118716-A | TOLNAFTATE GEL FOR EXTERNAL USE | NIPPON ZOKI PHARMACEUT CO LTD | 1986-01-27 | — | — | JP | disclosed |