Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665996 | 0.92 | POLB (0.38) | POLBKMT2AMEN1CA12CA1 | |
| SCHEMBL8667289 | 0.88 | ALDH1A1 (0.40) | POLBL3MBTL1KMT2AMEN1TAS1R3 | |
| SCHEMBL8666644 | 0.87 | LMNA (0.43) | POLBL3MBTL1KMT2AMEN1TAS1R3 | |
| SCHEMBL8669042 | 0.86 | ALDH1A1 (0.34) | POLBKMT2AHTT | |
| SCHEMBL8670553 | 0.85 | ALDH1A1 (0.38) | POLBL3MBTL1KMT2AMEN1TAS1R3 | |
| SCHEMBL8670484 | 0.83 | KCNK3 (0.41) | POLBKMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL8668472 | 0.80 | AR (0.32) | POLBL3MBTL1MAPTUSP2 | |
| SCHEMBL8669025 | 0.79 | PTGS1 (0.35) | POLBL3MBTL1 | |
| SCHEMBL8666674 | 0.77 | — | — | |
| SCHEMBL8670754 | 0.73 | MAPT (0.44) | POLBL3MBTL1KMT2AMEN1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750552-A | ANTIULCER AGENTS | ARAX CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |