Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | MDM4 | O15151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669042 | 0.88 | ALDH1A1 (0.34) | POLBHPGDLMNACYP2C19MAPK1 | |
| SCHEMBL8667289 | 0.86 | ALDH1A1 (0.40) | POLBMAPTKMT2A | |
| SCHEMBL8665996 | 0.84 | POLB (0.38) | POLBMAPTKMT2A | |
| SCHEMBL8670553 | 0.84 | ALDH1A1 (0.38) | POLBHPGDLMNAMAPTHDAC3 | |
| SCHEMBL8665904 | 0.83 | POLB (0.44) | POLBMAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL8666644 | 0.82 | LMNA (0.43) | POLBLMNAKMT2A | |
| SCHEMBL8659987 | 0.77 | KCNK3 (0.42) | KCNK3KCNK9NR1H4POLBHPGD | |
| SCHEMBL8654927 | 0.70 | KCNK3 (0.42) | KCNK3KCNK9NR1H4POLBHPGD | |
| SCHEMBL528445 | 0.67 | KCNK3 (0.77) | KCNK3KCNK9NR1H4POLBHPGD | |
| SCHEMBL6971074 | 0.66 | NR1H4 (0.57) | KCNK3KCNK9NR1H4POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750552-A | ANTIULCER AGENTS | ARAX CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0736527-A1 | Imadazoline derivative, possible tautomer thereof, process of manufacturing therefor, and vulnerary including such derivative or tautomer | ARAX CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |