Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667289 | 0.89 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2HTTGAAPOLB | |
| SCHEMBL8670484 | 0.88 | KCNK3 (0.41) | HPGDMAPK1LMNAPOLBCYP2C19 | |
| SCHEMBL8665996 | 0.87 | POLB (0.38) | ALDH1A1HTTGAAPOLBKMT2A | |
| SCHEMBL8670553 | 0.86 | ALDH1A1 (0.38) | ALDH1A1HPGDMAPK1KDM4ELMNA | |
| SCHEMBL8665904 | 0.86 | POLB (0.44) | HTTPOLBKMT2A | |
| SCHEMBL8667078 | 0.86 | SLC29A1 (0.37) | ALDH1A1LMNATSHRSMN1; SMN2POLB | |
| SCHEMBL8668472 | 0.85 | AR (0.32) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL8666644 | 0.85 | LMNA (0.43) | ALDH1A1KDM4ELMNASMN1; SMN2POLB | |
| SCHEMBL8669025 | 0.82 | PTGS1 (0.35) | ALDH1A1HPGDKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL8665811 | 0.81 | PSIP1 (0.36) | ALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750552-A | ANTIULCER AGENTS | ARAX CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0736527-A1 | Imadazoline derivative, possible tautomer thereof, process of manufacturing therefor, and vulnerary including such derivative or tautomer | ARAX CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |