Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669434 | 0.94 | ALDH1A1 (0.40) | MAPTLMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8669025 | 0.86 | PTGS1 (0.35) | ALDH1A1SMN1; SMN2POLBL3MBTL1KDM4E | |
| SCHEMBL8665811 | 0.85 | PSIP1 (0.36) | MAPTALDH1A1POLBTSHR | |
| SCHEMBL8668472 | 0.81 | AR (0.32) | MAPTALDH1A1POLBUSP2L3MBTL1 | |
| SCHEMBL8670484 | 0.76 | KCNK3 (0.41) | MAPTLMNAKMT2ACYP2C19POLB | |
| SCHEMBL8668788 | 0.73 | ATP4A (0.30) | — | |
| SCHEMBL8666644 | 0.73 | LMNA (0.43) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9141729 | 0.70 | ALDH1A1 (0.70) | MAPTLMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8666979 | 0.70 | MGLL (0.45) | MAPTLMNAMEN1KMT2A | |
| SCHEMBL8665501 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750552-A | ANTIULCER AGENTS | ARAX CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0736527-A1 | Imadazoline derivative, possible tautomer thereof, process of manufacturing therefor, and vulnerary including such derivative or tautomer | ARAX CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |