Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666893 | 0.80 | PTGS2 (0.39) | PTGS2DHODHCYP1A2GAACYP2C9 | |
| SCHEMBL25147202 | 0.75 | MC4R (0.42) | PDE3BPDE3ANR1H2NR1H3 | |
| SCHEMBL8666707 | 0.75 | COMT (0.42) | PTGS2DHODHPDE3BPDE3AKMT2A | |
| SCHEMBL6976337 | 0.69 | HPGD (0.38) | PDE3BPDE3ANR1H2NR1H3 | |
| SCHEMBL2278129 | 0.69 | PDE3B (0.37) | CYP1A2GAAPDE3BPDE3ANR1H2 | |
| SCHEMBL2224580 | 0.69 | TAAR1 (0.42) | PDE3BPDE3AKMT2ANR1H2NR1H3 | |
| SCHEMBL8666896 | 0.68 | KDM4E (0.44) | PTGS2DHODHGAAMEN1KMT2A | |
| SCHEMBL8666701 | 0.68 | KDM4E (0.44) | PTGS2DHODHCYP1A2GAAMEN1 | |
| SCHEMBL11564097 | 0.67 | GABRA2 (0.46) | DHODHCYP1A2PDE3BPDE3ANR1H2 | |
| SCHEMBL4416813 | 0.67 | BRD4 (0.48) | PTGS2DHODHCYP1A2PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811445-A | ANGIOTENSIN II INHIBITORS | ROUSSEL UCLAF (FR) | 1998-09-22 | — | — | US | disclosed |