Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 5/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666701 | 0.79 | KDM4E (0.44) | KDM4EHPGDSMN1; SMN2DHODHPDE2A | |
| SCHEMBL8666901 | 0.68 | PTGS2 (0.42) | DHODHGAAKMT2AMEN1PTGS2 | |
| SCHEMBL5763126 | 0.67 | KDM4E (0.58) | KDM4EHPGDSMN1; SMN2DHODHALDH1A1 | |
| SCHEMBL8666893 | 0.67 | PTGS2 (0.39) | DHODHGAAKMT2AMEN1PTGS2 | |
| SCHEMBL8666707 | 0.67 | COMT (0.42) | DHODHKMT2APTGS2 | |
| SCHEMBL24427668 | 0.65 | KDM4E (0.54) | KDM4EHPGDSMN1; SMN2DHODHALDH1A1 | |
| SCHEMBL5850257 | 0.64 | KDM4E (0.68) | KDM4EHPGDSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL3435446 | 0.63 | PTPN5 (0.46) | PTGS2 | |
| SCHEMBL1068923 | 0.63 | KDM4E (1.00) | KDM4EHPGDSMN1; SMN2ALDH1A1GLA | |
| Methyl Alcohol SCHEMBL5139174 | 0.63 | SRC (0.46) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811445-A | ANGIOTENSIN II INHIBITORS | ROUSSEL UCLAF (FR) | 1998-09-22 | — | — | US | disclosed |