Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665904 | 0.94 | POLB (0.44) | POLBL3MBTL1HTTUSP2EPHX1 | |
| SCHEMBL8665996 | 0.90 | POLB (0.38) | POLBHTTALDH1A1MEN1KMT2A | |
| SCHEMBL8667289 | 0.86 | ALDH1A1 (0.40) | POLBL3MBTL1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8666644 | 0.86 | LMNA (0.43) | POLBL3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8669042 | 0.84 | ALDH1A1 (0.34) | POLBHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8670553 | 0.83 | ALDH1A1 (0.38) | POLBL3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8670484 | 0.81 | KCNK3 (0.41) | POLBLMNAKMT2AHPGDATM | |
| SCHEMBL8668472 | 0.78 | AR (0.32) | POLBL3MBTL1USP2ALDH1A1KDM4E | |
| SCHEMBL8669025 | 0.78 | PTGS1 (0.35) | POLBL3MBTL1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8666674 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750552-A | ANTIULCER AGENTS | ARAX CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0736527-A1 | Imadazoline derivative, possible tautomer thereof, process of manufacturing therefor, and vulnerary including such derivative or tautomer | ARAX CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |