SCHEMBL8667201

SCHEMBL8667201

CS(=O)(=O)c1nc(Br)cc(Br)n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.56
SMN1; SMN2 Q16637 7/20 0.56
BPTF Q12830 2/20 0.37
NPSR1 Q6W5P4 7/20 0.36
HPGD P15428 6/20 0.36
SDHB P21912 5/20 0.36
KMT2A Q03164 5/20 0.36
TP53 P04637 5/20 0.36
HTT P42858 5/20 0.36
RAB9A P51151 4/20 0.36
STAT3 P40763 4/20 0.36
HSD17B10 Q99714 4/20 0.36
STAT1 P42224 2/20 0.36
TLR9 Q9NR96 2/20 0.36
S1PR4 O95977 2/20 0.36
S1PR1 P21453 2/20 0.36
MAPK1 P28482 2/20 0.36
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36
HTR6 P50406 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11107779 0.85 LMNA (0.47) LMNASMN1; SMN2BPTFNPSR1HPGD
SCHEMBL28660457 0.80 LMNA (0.43) LMNASMN1; SMN2BPTFHTR6
SCHEMBL1578806 0.75 HTR6 (0.48) LMNASMN1; SMN2HTR6PLCG1
SCHEMBL7753780 0.74 LMNA (0.52) LMNASMN1; SMN2BPTFNPSR1HPGD
SCHEMBL20606050 0.73 LMNA (0.39) LMNASMN1; SMN2BPTFNPSR1TP53
SCHEMBL9626200 0.72 LMNA (0.52) LMNASMN1; SMN2BPTFNPSR1HPGD
SCHEMBL1051087 0.72 LMNA (0.52) LMNASMN1; SMN2BPTFNPSR1HPGD
SCHEMBL1067726 0.71 SMN1; SMN2 (1.00) LMNASMN1; SMN2BPTFNPSR1HPGD
SCHEMBL63292 0.70 LMNA (0.50) LMNASMN1; SMN2BPTFNPSR1HPGD
SCHEMBL28024889 0.70 LMNA (0.50) LMNASMN1; SMN2BPTFNPSR1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5723412-A HERBICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-03-03 US disclosed
US-5599770-A WEED CONTROL; INCLUDING AN ADJUVANT KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-02-04 US disclosed
EP-0694538-A2 2-benzyloxy-4-phenoxypyrimidine derivative, processes for producing the derivative and herbicidal composition containing the derivative KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-01-31 EP disclosed
EP-0692477-A1 Herbicidal compositions containing 2-benzyloxypyrimidine derivatives KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-01-17 EP disclosed