Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961983 | 0.81 | ALDH1A1 (0.51) | RAB9ASMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL4603679 | 0.78 | SMN1; SMN2 (0.74) | RAB9ASMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL16383886 | 0.76 | SMN1; SMN2 (0.77) | RAB9ASMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL9002518 | 0.73 | F10 (0.72) | RAB9ASMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL15120766 | 0.73 | HSD17B10 (0.68) | RAB9ASMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL1707707 | 0.72 | SMN1; SMN2 (0.75) | RAB9ASMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL19268078 | 0.71 | KMT2A (0.54) | RAB9ASMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL27469650 | 0.71 | HCAR2 (0.59) | RAB9ASMN1; SMN2ALDH1A1KDM4EKMT2A | |
| Bromide SCHEMBL7622448 | 0.70 | HCAR2 (0.57) | RAB9ASMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL10073854 | 0.70 | HSD17B10 (0.64) | RAB9ASMN1; SMN2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726306-A | INHIBITORS OF SQUALENE SYNTHETASE AND FUNGAL GROWTH; USEFUL IN TREATING AND PREVENTING HYPERLIPIDEMIA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-10 | — | — | US | disclosed |