Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550780 | 0.89 | RXRA (0.37) | CACNA1DPTGDR2CNR2USP2 | |
| SCHEMBL8552335 | 0.86 | CACNA1D (0.33) | CACNA1DPTGDR2 | |
| SCHEMBL8672349 | 0.84 | TLR8 (0.39) | TLR8MEN1KMT2ATDP1 | |
| SCHEMBL8668302 | 0.83 | CACNA1D (0.35) | CACNA1DPTGDR2MEN1KMT2AHTR2B | |
| SCHEMBL8672721 | 0.83 | PTGS2 (0.40) | MEN1KMT2APKM | |
| SCHEMBL8667814 | 0.78 | HTR2B (0.34) | CACNA1DPTGDR2MEN1KMT2AHTR2B | |
| SCHEMBL8551852 | 0.75 | NCF1 (0.33) | MEN1KMT2AKDM4E | |
| SCHEMBL8668305 | 0.73 | MEN1 (0.34) | CACNA1DPTGDR2MEN1KMT2AHTR2B | |
| SCHEMBL8547164 | 0.73 | TDP1 (0.38) | KDM4ETDP1 | |
| SCHEMBL8553294 | 0.71 | S1PR4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840910-A | Pyridine derivatives having anti-ulcerative activity | ESAI CO., LTD. (JP) | 1998-11-24 | — | — | US | disclosed |