SCHEMBL866841

SCHEMBL866841

c1ccc(-c2ccccc2-c2ccc(-c3cccc4c3[nH]c3ccccc34)cc2)c(-c2ccc(-c3cccc4c3[nH]c3ccccc34)cc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.53
PARP14 Q460N5 10/20 0.49
ALDH1A1 P00352 1/20 0.48
GPR3 P46089 1/20 0.48
HSD17B10 Q99714 1/20 0.48
BCHE P06276 1/20 0.47
GABRP O00591 1/20 0.47
GABRD O14764 1/20 0.47
GABRA1 P14867 1/20 0.47
GABRB1 P18505 1/20 0.47
GABRG2 P18507 1/20 0.47
GABRB3 P28472 1/20 0.47
GABRA5 P31644 1/20 0.47
GABRA3 P34903 1/20 0.47
GABRA2 P47869 1/20 0.47
GABRB2 P47870 1/20 0.47
GABRA4 P48169 1/20 0.47
GABRE P78334 1/20 0.47
GABRA6 Q16445 1/20 0.47
GABRG1 Q8N1C3 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30059288 1.00 KIF11 (0.53) KIF11PARP14ALDH1A1GPR3HSD17B10
SCHEMBL1326378 0.98 KIF11 (0.55) KIF11PARP14ALDH1A1GPR3HSD17B10
SCHEMBL29407801 0.96 KIF11 (0.57) KIF11PARP14ALDH1A1GPR3HSD17B10
SCHEMBL30641449 0.96 KIF11 (0.57) KIF11PARP14ALDH1A1GPR3HSD17B10
SCHEMBL1326376 0.96 KIF11 (0.57) KIF11PARP14ALDH1A1GPR3HSD17B10
SCHEMBL208888 0.96 KIF11 (0.57) KIF11PARP14ALDH1A1GPR3HSD17B10
SCHEMBL38828 0.96 KIF11 (0.57) KIF11PARP14ALDH1A1GPR3HSD17B10
SCHEMBL27947473 0.94 CDK4 (0.53) KIF11PARP14ALDH1A1GPR3HSD17B10
SCHEMBL17969001 0.92 CDK4 (0.54) KIF11PARP14ALDH1A1GPR3HSD17B10
SCHEMBL30985273 0.92 CDK4 (0.54) KIF11PARP14ALDH1A1GPR3HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940408-B2 White organic light-emitting device INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2015-01-27 US claimed
US-8319421-B2 Organic light-emitting laminate and organic electroluminescent device containing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2012-11-27 US claimed
US-20100314612-A1 WHITE ORGANIC LIGHT-EMITTING DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-12-16 US claimed
US-20090295278-A1 Organic light-emitting laminate and organic electroluminescent device conatiaing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2009-12-03 US claimed
US-10786683-B2 Light-emitting devices for wound healing NITTO DENKO CORPORATION (JP) 2020-09-29 US disclosed
US-9978953-B2 Substituted biphenyl compounds for use in light-emitting devices NITTO DENKO CORPORATION (JP) 2018-05-22 US disclosed
US-9917281-B2 Top-emitting white organic light-emitting diodes having improved efficiency and stability NITTO DENKO CORPORATION (JP) 2018-03-13 US disclosed
EP-2681970-B1 POROUS FILMS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORP (JP) 2018-01-17 EP disclosed
US-9859517-B2 White organic light-emitting diode NITTO DENKO CORPORATION (JP) 2018-01-02 US disclosed
US-9853220-B2 Efficient organic light-emitting diodes and fabrication of the same NITTO DENKO CORPORATION (JP) 2017-12-26 US disclosed
EP-2723721-B1 POLYPHENYLENE HOST COMPOUNDS NITTO DENKO CORP (JP) 2017-08-09 EP disclosed
US-9614162-B2 Light-emitting devices comprising emissive layer NITTO DENKO CORPORATION (JP) 2017-04-04 US disclosed
US-20120179089-A1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-07-12 US disclosed
US-20120121933-A1 HYBRID COMPOSITE EMISSIVE CONSTRUCT AND LIGHT-EMITTING DEVICES USING THE SAME NITTO DENKO CORPORATION (JP) 2012-05-17 US disclosed
US-20120075278-A1 ORGANIC EL DISPLAY KABUSHIKI KAISHA TOSHIBA (JP) 2012-03-29 US disclosed
US-20110251401-A1 POLYPHENYLENE HOST COMPOUNDS NITTO DENKO CORPORATION (JP) 2011-10-13 US disclosed
US-20110196158-A1 TRIS(ARYLBENZOXAZOLE)BENZENE AND TRIS(ARYLBENZTHIAZOLE)BENZENE AND DERIVATIVES THEREOF AS ORGANIC ELECTRON-TRANSPORT MATERIALS Nitto Denko Technical Corporation (JP) 2011-08-11 US disclosed
US-20110140093-A1 COMPOUNDS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2011-06-16 US disclosed
US-20100314612-A1 WHITE ORGANIC LIGHT-EMITTING DEVICE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-12-16 US disclosed
US-20090295278-A1 Organic light-emitting laminate and organic electroluminescent device conatiaing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2009-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110196158-A1 TRIS(ARYLBENZOXAZOLE)BENZENE AND TRIS(ARYLBENZTHIAZOLE)BENZENE AND DERIVATIVES THEREOF AS ORGANIC ELECTRON-TRANSPORT MATERIALS ARNT, CYP1A1, AHR KIF11 3428/4885PARP14 1097/4885ALDH1A1 155/4885
US-20110251401-A1 POLYPHENYLENE HOST COMPOUNDS PPOX, PPIL1, PIN1 KIF11 2645/4885PARP14 2626/4885ALDH1A1 920/4885
US-20110140093-A1 COMPOUNDS FOR USE IN LIGHT-EMITTING DEVICES NR2E3, CYP3A4, UGT1A4 KIF11 3931/4885PARP14 860/4885ALDH1A1 94/4885
US-20120179089-A1 SUBSTITUTED BIPYRIDINES FOR USE IN ORGANIC LIGHT-EMITTING DEVICES BRD9, PIR, BRD2 KIF11 3185/4885PARP14 433/4885ALDH1A1 867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.