SCHEMBL8668649

SCHEMBL8668649

CCCCCO[SiH](OCCCCC)C(C)C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.32
DNM1 Q05193 1/20 0.31
SPHK1 Q9NYA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8666602 0.94 ADRB2 (0.32)
SCHEMBL8665526 0.85 HSD17B10 (0.30)
SCHEMBL28994579 0.74 DNM1 (0.33) CES1DNM1SPHK1
SCHEMBL28898369 0.72 OPRM1 (0.34) DNM1SPHK1
SCHEMBL705118 0.70 ADRB2 (0.38)
SCHEMBL27819229 0.69 CES1 (0.36) CES1
SCHEMBL28516102 0.67 DNM1 (0.34) CES1DNM1SPHK1
SCHEMBL11250053 0.67 ADRB2 (0.35)
SCHEMBL2772303 0.67 ADRB2 (0.35)
SCHEMBL4388494 0.67 DNM1 (0.39) DNM1SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530814-B1 Method for producing a stereospecific polyolefin TOSOH CORP (JP) 1998-12-16 EP disclosed
US-5489634-A EFFICIENT SELECTIVE CATALYTIC POLYMERIZATION OF ALPHA-OLEFINS YIELDS HIGH MOLECULAR WEIGHT SPHERICAL PARTICLES HAVING HIGH BULK DENSITY, CONTROLLED PARTICLE SIZE AND MOLECULAR WEIGHT DISTRIBUTION TOSOH CORPORATION (JP) 1996-02-06 US disclosed
EP-0582943-A2 Method for producing a polyolefin TOSOH CORPORATION (JP) 1994-02-16 EP disclosed
EP-0530814-A1 Method for producing a stereospecific polyolefin TOSOH CORPORATION (JP) 1993-03-10 EP disclosed