Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672201 | 0.83 | ALOX15 (0.39) | ALOX15ALDH1A1TNFKDM4EMAPT | |
| SCHEMBL8671445 | 0.83 | KDM4E (0.39) | ALOX15ALDH1A1TNFKDM4EMAPT | |
| SCHEMBL8669828 | 0.78 | KMT2A (0.49) | ALOX15ALDH1A1FPR2KMT2AMAPT | |
| SCHEMBL8670242 | 0.77 | CYP1A1 (0.40) | ALOX15ALDH1A1FPR2KMT2ATNF | |
| SCHEMBL8668930 | 0.76 | MTNR1A (0.60) | ALOX15ALDH1A1FPR2KMT2ATNF | |
| SCHEMBL8673938 | 0.76 | MTNR1A (0.52) | ALOX15ALDH1A1KMT2AMEN1MTNR1A | |
| SCHEMBL8668238 | 0.76 | TACR1 (0.43) | ALOX15TNFKDM4EMAPTTHRB | |
| SCHEMBL20561813 | 0.73 | MTNR1A (0.49) | SMN1; SMN2LMNAMTNR1AMTNR1B | |
| SCHEMBL3419160 | 0.70 | LDHA (0.66) | ALOX15ALDH1A1FPR2KMT2AITGB3 | |
| SCHEMBL2516039 | 0.70 | LDHA (0.66) | ALOX15ALDH1A1FPR2KMT2AITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849781-A | Tricyclic amides | ADIR ET COMPAGNIE (FR) | 1998-12-15 | — | — | US | disclosed |
| US-5712312-A | MELATONINERGIC RECEPTOR LIGANDS, TREATMENT OF SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1998-01-27 | — | — | US | disclosed |