Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666332 | 0.79 | ACE (0.54) | ACEDPP4DPP8DPP7MEN1 | |
| SCHEMBL8671884 | 0.75 | ACE (0.46) | ACETSHRDPP4DPP8DPP7 | |
| SCHEMBL8667007 | 0.71 | POLB (0.44) | ACEMEN1HTTKMT2APOLB | |
| SCHEMBL8669414 | 0.71 | SIGMAR1 (0.43) | ACE | |
| SCHEMBL8668286 | 0.70 | ITGB1 (0.44) | ACESMN1; SMN2ALDH1A1 | |
| SCHEMBL8667711 | 0.68 | ACE (0.41) | ACEDPP4DPP8DPP7MEN1 | |
| SCHEMBL7775338 | 0.66 | FFAR2 (0.48) | ACEFFAR2 | |
| SCHEMBL8869991 | 0.66 | FFAR2 (0.48) | ACEFFAR2 | |
| SCHEMBL7775333 | 0.66 | FFAR2 (0.48) | ACEFFAR2 | |
| SCHEMBL8667689 | 0.66 | GPR88 (0.35) | ACEMEN1KMT2AFFAR2AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |