Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 4/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGAV | P06756 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667007 | 0.85 | POLB (0.44) | L3MBTL1ALDH1A1LMNAACESMN1; SMN2 | |
| SCHEMBL8666332 | 0.81 | ACE (0.54) | ALDH1A1LMNAACE | |
| SCHEMBL8671884 | 0.77 | ACE (0.46) | ACE | |
| SCHEMBL8669414 | 0.74 | SIGMAR1 (0.43) | ACE | |
| SCHEMBL8668940 | 0.70 | ACE (0.41) | ALDH1A1ACESMN1; SMN2 | |
| SCHEMBL8667711 | 0.69 | ACE (0.41) | ALDH1A1ACESMN1; SMN2 | |
| SCHEMBL2498591 | 0.69 | ALDH1A1 (0.64) | ITGB1ITGA5ITGA4ITGB3ITGAV | |
| SCHEMBL8672106 | 0.68 | LMNA (0.37) | L3MBTL1ALDH1A1LMNAACE | |
| SCHEMBL8671320 | 0.68 | SIGMAR1 (0.41) | ACESMN1; SMN2HPGD | |
| SCHEMBL8668993 | 0.68 | TSHR (0.44) | L3MBTL1ALDH1A1LMNASMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |