Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 7/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667711 | 0.87 | ACE (0.41) | SIGMAR1ACEHRH3 | |
| SCHEMBL8666332 | 0.86 | ACE (0.54) | ACE | |
| SCHEMBL8671884 | 0.79 | ACE (0.46) | SIGMAR1ACE | |
| SCHEMBL8667007 | 0.78 | POLB (0.44) | ACE | |
| SCHEMBL8672121 | 0.78 | SIGMAR1 (0.45) | SIGMAR1ACEPREPHRH3 | |
| SCHEMBL8668716 | 0.77 | FKBP1A (0.39) | — | |
| SCHEMBL8668286 | 0.74 | ITGB1 (0.44) | ACE | |
| SCHEMBL8668940 | 0.71 | ACE (0.41) | ACE | |
| SCHEMBL3656053 | 0.71 | SIGMAR1 (0.66) | SIGMAR1PREPHRH3 | |
| SCHEMBL10123280 | 0.70 | SIGMAR1 (0.76) | SIGMAR1PREPHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |