Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.56 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL8669137 | 1.00 | FABP3 (0.56) | FABP3SLC6A5EPHX2FAAHMEN1 | |
| Potassium Ion SCHEMBL5597233 | 1.00 | FABP3 (0.56) | FABP3SLC6A5EPHX2FAAHMEN1 | |
| Potassium Ion SCHEMBL5597298 | 1.00 | FABP3 (0.56) | FABP3SLC6A5EPHX2FAAHMEN1 | |
| Potassium Ion SCHEMBL1534741 | 1.00 | FABP3 (0.56) | FABP3SLC6A5EPHX2FAAHMEN1 | |
| Potassium Ion SCHEMBL5597299 | 1.00 | FABP3 (0.56) | FABP3SLC6A5EPHX2FAAHMEN1 | |
| Potassium Ion SCHEMBL5690557 | 1.00 | FABP3 (0.56) | FABP3SLC6A5EPHX2FAAHMEN1 | |
| Potassium Ion SCHEMBL2139388 | 1.00 | FABP3 (0.56) | FABP3SLC6A5EPHX2FAAHMEN1 | |
| Potassium Ion SCHEMBL1534743 | 1.00 | FABP3 (0.56) | FABP3SLC6A5EPHX2FAAHMEN1 | |
| Potassium Ion SCHEMBL5690504 | 1.00 | FABP3 (0.56) | FABP3SLC6A5EPHX2FAAHMEN1 | |
| Potassium Ion SCHEMBL5597232 | 1.00 | FABP3 (0.56) | FABP3SLC6A5EPHX2FAAHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10324721-A | — | — | None | — | — | JP | disclosed |
| JP-H10324721-A | GRAFT COPOLYMER AND RUBBER-MODIFIED THERMOPLASTIC RESIN COMPOSITION | KANEGAFUCHI CHEM IND CO LTD | 1998-12-08 | — | — | JP | disclosed |