Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870968 | 0.87 | MMP2 (0.41) | CYP2C19KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL8870976 | 0.87 | MMP2 (0.41) | CYP2C19KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL8870755 | 0.82 | CYP3A4 (0.37) | MMP3MMP8CYP2C19CYP2D6KMT2A | |
| SCHEMBL8870760 | 0.82 | CYP3A4 (0.37) | MMP3MMP8CYP2C19CYP2D6KMT2A | |
| SCHEMBL8871034 | 0.82 | KMT2A (0.38) | MMP3MMP8CYP2C19CYP2D6KMT2A | |
| SCHEMBL8666857 | 0.82 | KMT2A (0.38) | MMP3MMP8CYP2C19CYP2D6KMT2A | |
| SCHEMBL8871401 | 0.81 | P4HTM (0.35) | MMP3MMP8CYP2C19CYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL8666991 | 0.81 | KMT2A (0.37) | MMP3MMP8CYP2C19CYP2D6KMT2A | |
| SCHEMBL8871412 | 0.81 | P4HTM (0.35) | MMP3MMP8CYP2C19CYP2D6KMT2A | |
| SCHEMBL8685324 | 0.75 | L3MBTL1 (0.38) | MMP3MMP8KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |