Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871412 | 1.00 | P4HTM (0.35) | P4HTMPTGS2MMP3MMP8ALDH1A1 | |
| SCHEMBL8669917 | 0.81 | MMP3 (0.39) | MMP3MMP8ALDH1A1KDM4EHPGD | |
| SCHEMBL8870755 | 0.76 | CYP3A4 (0.37) | MMP3MMP8LMNARAB9AALOX15 | |
| SCHEMBL8870760 | 0.76 | CYP3A4 (0.37) | MMP3MMP8LMNARAB9AALOX15 | |
| SCHEMBL8871034 | 0.76 | KMT2A (0.38) | MMP3MMP8ALDH1A1HPGDKAT6A | |
| SCHEMBL8666857 | 0.76 | KMT2A (0.38) | MMP3MMP8ALDH1A1HPGDKAT6A | |
| Hydrochloric Acid SCHEMBL8666991 | 0.75 | KMT2A (0.37) | MMP3MMP8ALDH1A1HPGDKAT6A | |
| SCHEMBL8870976 | 0.73 | MMP2 (0.41) | ALDH1A1SMN1; SMN2KAT6ALMNAMEN1 | |
| SCHEMBL8870968 | 0.73 | MMP2 (0.41) | ALDH1A1SMN1; SMN2KAT6ALMNAMEN1 | |
| SCHEMBL6633356 | 0.72 | KDM4E (0.37) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |