Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870968 | 1.00 | MMP2 (0.41) | MMP2KMT2AMEN1KAT6AALDH1A1 | |
| SCHEMBL8669917 | 0.87 | MMP3 (0.39) | MMP2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8870760 | 0.79 | CYP3A4 (0.37) | MMP2KMT2AMEN1LMNACYP2C19 | |
| SCHEMBL8870755 | 0.79 | CYP3A4 (0.37) | MMP2KMT2AMEN1LMNACYP2C19 | |
| SCHEMBL8685324 | 0.74 | L3MBTL1 (0.38) | KMT2AMEN1MAPTUSP2 | |
| SCHEMBL8871034 | 0.74 | KMT2A (0.38) | MMP2KMT2AMEN1KAT6AALDH1A1 | |
| SCHEMBL8666857 | 0.74 | KMT2A (0.38) | MMP2KMT2AMEN1KAT6AALDH1A1 | |
| SCHEMBL8871401 | 0.73 | P4HTM (0.35) | KMT2AMEN1KAT6AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8666991 | 0.73 | KMT2A (0.37) | KMT2AMEN1KAT6AALDH1A1LMNA | |
| SCHEMBL8871412 | 0.73 | P4HTM (0.35) | KMT2AMEN1KAT6AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |