Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | CDK14 | O94921 | 8/20 | 0.35 |
| ▸ | CCNY | Q8ND76 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597839 | 0.91 | TYK2 (0.36) | CDK14CCNYTYK2HSD17B10TSHR | |
| SCHEMBL8598882 | 0.76 | TYK2 (0.44) | ALDH1A1MAPTTYK2PTGES | |
| SCHEMBL8596974 | 0.73 | TYK2 (0.38) | ALDH1A1MAPTTYK2 | |
| Hydrochloric Acid SCHEMBL8600669 | 0.73 | TYK2 (0.38) | ALDH1A1MAPTTYK2PTGES | |
| SCHEMBL8670351 | 0.67 | KDM4E (0.33) | MAPK8MAPK10CDK14CCNYALDH1A1 | |
| SCHEMBL8596742 | 0.66 | PTGES (0.36) | CDK14CCNYTYK2TSHRPTGES | |
| SCHEMBL8670583 | 0.65 | TSHR (0.35) | CDK14CCNYALDH1A1MAPTHSD17B10 | |
| SCHEMBL8670347 | 0.64 | MAPT (0.48) | ALDH1A1MAPTKDM4EPTGES | |
| SCHEMBL8670346 | 0.64 | PTGES (0.36) | MAPK8MAPK10CDK14CCNYLMNA | |
| Hydrochloric Acid SCHEMBL9081087 | 0.63 | MEN1 (0.39) | MAPK8MAPK10CDK14CCNYALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |