Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | CDK14 | O94921 | 4/20 | 0.32 |
| ▸ | CCNY | Q8ND76 | 4/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597843 | 0.91 | TYK2 (0.35) | MAPTTYK2PTGESPDE4BRORC | |
| SCHEMBL8598885 | 0.77 | TYK2 (0.44) | TYK2PTGESPDE4BRORCRAB9A | |
| SCHEMBL8596977 | 0.75 | TYK2 (0.38) | KDM4EALDH1A1TYK2PDE4BRORC | |
| SCHEMBL8597247 | 0.75 | LCK (0.37) | TYK2PTGESPDE4BLMNARORC | |
| Hydrochloric Acid SCHEMBL8600677 | 0.74 | TYK2 (0.37) | KDM4EALDH1A1TYK2PDE4BRORC | |
| SCHEMBL8670347 | 0.68 | MAPT (0.48) | KDM4EALDH1A1MAPTPTGES | |
| SCHEMBL8670346 | 0.68 | PTGES (0.36) | MAPTTYK2PTGESCDK14CCNY | |
| SCHEMBL8670342 | 0.67 | MAPK8 (0.36) | KDM4EALDH1A1MAPTTYK2PTGES | |
| SCHEMBL8601990 | 0.65 | KMT2A (0.40) | MAPTTYK2PTGESPDE4BLMNA | |
| SCHEMBL8598365 | 0.62 | TYK2 (0.44) | TYK2PTGESPDE4BSMN1; SMN2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |