Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667734 | 0.83 | HPGD (0.35) | HPGDKDM4EHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8669816 | 0.70 | AR (0.38) | HPGDKDM4EHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8439253 | 0.70 | MAPT (0.41) | HPGDKDM4EHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8633727 | 0.69 | MAPT (0.41) | HPGDKDM4EHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8500399 | 0.69 | ALDH1A1 (0.35) | HPGDKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL8503831 | 0.68 | MAPT (0.39) | HPGDKDM4EHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8672637 | 0.65 | SMN1; SMN2 (0.37) | HPGDKDM4EHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8501995 | 0.64 | RAB9A (0.43) | HPGDHSD17B10SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8670481 | 0.64 | ALDH1A1 (0.36) | HPGDKDM4EHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL8503176 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840910-A | Pyridine derivatives having anti-ulcerative activity | ESAI CO., LTD. (JP) | 1998-11-24 | — | — | US | disclosed |