Sulfuric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 CALCRL CHRM1 CHRM2 CHRM3 F2R MAOA MAOB MAP2K1 MAP2K2 NTRK1 NTRK2 NTRK3 OPRD1 OPRK1 OPRM1 P2RY12 PKLR SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SLC18A2 SLC6A2 SLC6A3 TLR7 TLR9 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 dacA dacB dacC folA ftsI mrcA mrcB mrdA pol rplA rplB rplC rplD rplE rplF rplI rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmB1 rpmB2 rpmC rpmD rpmE rpmE2 rpmF rpmG rpmG1 rpmG2 rpmH rpmI rpmJ rpmJ2 rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsR1 rpsR2 rpsS rpsT rpsU rpsZ ykgM ykgO

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	CA5A	P35218	2/20	0.67

▸	CA5B	Q9Y2D0	2/20	0.67

▸	KDM4E	B2RXH2	3/20	0.50

▸	CYP3A4	P08684	2/20	0.50

▸	CA2	P00918	3/20	0.43

▸	TSHR	P16473	4/20	0.42

▸	CA1	P00915	2/20	0.42

▸	NT5E	P21589	1/20	0.42

▸	CA4	P22748	1/20	0.42

▸	CA6	P23280	1/20	0.42

▸	CA7	P43166	1/20	0.42

▸	CA9	Q16790	1/20	0.42

▸	TDP1	Q9NUW8	1/20	0.42

▸	BLM	P54132	2/20	0.40

▸	CYP2D6	P10635	1/20	0.39

▸	CYP2C19	P33261	1/20	0.39

▸	NPSR1	Q6W5P4	1/20	0.39

▸	ALDH1A1	P00352	2/20	0.39

▸	MEN1	O00255	1/20	0.39

▸	KMT2A	Q03164	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Sulfuric Acid SCHEMBL7201060	0.89	CA5A (0.67)	CA5ACA5BKDM4ECYP3A4CA2
Dimethyl Sulfone SCHEMBL16321746	0.89	KDM4E (0.67)	CA5ACA5BKDM4ECYP3A4CA2
Sulfuric Acid SCHEMBL676741	0.89	CA5A (0.67)	CA5ACA5BKDM4ECYP3A4CA2
Sulfuric Acid SCHEMBL17102613	0.89	CA5A (0.67)	CA5ACA5BKDM4ECYP3A4CA2
Sulfuric Acid SCHEMBL28003070	0.84	CA5A (0.60)	CA5ACA5BKDM4ECYP3A4CA2
Sulfuric Acid SCHEMBL4614990	0.84	CA5A (0.60)	CA5ACA5BKDM4ECYP3A4CA2
SCHEMBL15109974	0.82	—	—
SCHEMBL25599	0.82	CA2 (0.58)	CA5ACA5BKDM4ECYP3A4CA2
SCHEMBL105	0.82	—	—
Sulfuric Acid SCHEMBL17311240	0.82	CA5A (0.75)	CA5ACA5BKDM4ECYP3A4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5466816-A	Process for preparation of azolylmethylcycloalkanol derivatives	KUREHA CHEMICAL INDUSTRY CO., LTD. (JP)	1995-11-14	—	—	US	claimed
EP-0655443-A2	Process for the preparation of azolylmethylcycloalkanol derivatives	KUREHA CHEMICAL INDUSTRY CO., LTD. (JP)	1995-05-31	—	—	EP	claimed
US-20120108422-A1	Antifungal 1,2,4-triazolyl Derivatives	BASF SE (DE)	2012-05-03	—	—	US	disclosed
EP-2443098-A1	ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES	BASF SE (DE)	2012-04-25	—	—	EP	disclosed
EP-2443099-A1	ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES HAVING A 5- SULFUR SUBSTITUENT	BASF SE (DE)	2012-04-25	—	—	EP	disclosed
EP-2443097-A1	ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES	BASF SE (DE)	2012-04-25	—	—	EP	disclosed
EP-2440535-A1	ANTIFUNGAL 1,2,4-TRIAZOLYL DERIVATIVES HAVING A 5- SULFUR SUBSTITUENT	BASF SE (DE)	2012-04-18	—	—	EP	disclosed
US-20120088660-A1	Antifungal 1,2,4-triazolyl Derivatives	BASF SE (DE)	2012-04-12	—	—	US	disclosed
US-20120088664-A1	Antifungal 1,2,4-triazolyl derivatives having a 5-sulfur subtituent	BASF SE (DE)	2012-04-12	—	—	US	disclosed
US-20120077676-A1	Antifungal 1,2,4-Triazolyl Derivatives Having a 5-Sulfur Substituent	BASF SE (DE)	2012-03-29	—	—	US	disclosed
WO-2010149414-A1	5-MERCAPTO-[1, 2, 4] TRIAZOLYLMETHYL-CYCLOPENTANOL COMPOUNDS AND THEIR AGRICULTURAL AND PHARMACEUTICAL USES	BASF SE (DE)	2010-12-29	—	—	WO	disclosed
WO-2010146111-A1	ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES	BASF SE (DE)	2010-12-23	—	—	WO	disclosed
WO-2010146112-A1	ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES	BASF SE (DE)	2010-12-23	—	—	WO	disclosed
WO-2010142779-A1	ANTIFUNGAL 1,2,4-TRIAZOLYL DERIVATIVES HAVING A 5- SULFUR SUBSTITUENT	BASF SE (DE)	2010-12-16	—	—	WO	disclosed
WO-2010122171-A1	5-HETEROARYLMETHYL-I- (B-MERCAPTO- [1,2, 4 -TRIAZOLYLMETHYL) -CYCLOPENTANOL AS FUNGICIDES	BASF SE (DE)	2010-10-28	—	—	WO	disclosed
WO-2010122169-A1	5-MERCAPTO- [1,2, 4] TRIAZOLE COMPOUNDS AND THEIR AGRICULTURAL AND PHARMACEUTICAL USES	BASF SE (DE)	2010-10-28	—	—	WO	disclosed
WO-2010122167-A1	5 -MERCAPTO- [1, 2, 4] TRIAZOLYLMETHYL-CYCLOPENTANOL COMPOUNDS AND THEIR AGRICULTURAL AND PHARMACEUTICAL USES	BASF SE (DE)	2010-10-28	—	—	WO	disclosed
WO-2010122170-A1	5-MERCAPTO- [1,2,4] TRIAZOLYLMETHYL-CYCLOPENTANOL COMPOUNDS AND THEIR AGRICULTURAL AND PHARMACEUTI AL USES	BASF SE (DE)	2010-10-28	—	—	WO	disclosed
US-5466816-A	Process for preparation of azolylmethylcycloalkanol derivatives	KUREHA CHEMICAL INDUSTRY CO., LTD. (JP)	1995-11-14	—	—	US	disclosed
EP-0655443-A2	Process for the preparation of azolylmethylcycloalkanol derivatives	KUREHA CHEMICAL INDUSTRY CO., LTD. (JP)	1995-05-31	—	—	EP	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20120088660-A1	Antifungal 1,2,4-triazolyl Derivatives	ERG28, CYP51A1, DPM1	CA5A 939/4885CA5B 1209/4885KDM4E 1829/4885
US-20120088664-A1	Antifungal 1,2,4-triazolyl derivatives having a 5-sulfur subtituent	STS, TST, ERG28	CA5A 616/4885CA5B 818/4885KDM4E 1818/4885
US-20120108422-A1	Antifungal 1,2,4-triazolyl Derivatives	ERG28, CYP51A1, DPM1	CA5A 939/4885CA5B 1209/4885KDM4E 1829/4885
US-20120077676-A1	Antifungal 1,2,4-Triazolyl Derivatives Having a 5-Sulfur Substituent	ERG28, STS, CYP51A1	CA5A 698/4885CA5B 1073/4885KDM4E 1405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.