Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.34 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 4/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668357 | 0.94 | PARP14 (0.35) | PARP14ALDH1A1GAAMAPTBRD4 | |
| SCHEMBL8665811 | 0.91 | PSIP1 (0.36) | PARP14ALDH1A1MAPT | |
| SCHEMBL8669025 | 0.86 | PTGS1 (0.35) | HPGDKDM4EALDH1A1JAK1 | |
| SCHEMBL8666442 | 0.83 | NR3C1 (0.32) | — | |
| SCHEMBL8669434 | 0.83 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL8670754 | 0.81 | MAPT (0.44) | KDM4EALDH1A1GAAMAPTLMNA | |
| SCHEMBL8668472 | 0.80 | AR (0.32) | HPGDKDM4EALDH1A1MAPTAR | |
| SCHEMBL8667079 | 0.79 | POLB (0.53) | HPGDKDM4EALDH1A1LMNA | |
| SCHEMBL8668497 | 0.78 | — | — | |
| SCHEMBL8666674 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750552-A | ANTIULCER AGENTS | ARAX CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0736527-A1 | Imadazoline derivative, possible tautomer thereof, process of manufacturing therefor, and vulnerary including such derivative or tautomer | ARAX CO., LTD. (JP) | 1996-10-09 | — | — | EP | disclosed |