Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 7/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.40 |
| ▸ | CTSD | P07339 | 3/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927619 | 0.88 | CTRB1 (0.50) | CCR1MMEMMEL1BACE1CTRB1 | |
| SCHEMBL8670883 | 0.87 | MAPK1 (0.44) | CCR1BACE1NPC1RAB9A | |
| SCHEMBL8669429 | 0.81 | PSMB5 (0.44) | CCR1BACE1BACE2CTSD | |
| SCHEMBL8668860 | 0.80 | ATM (0.49) | BACE1 | |
| Hydrochloric Acid SCHEMBL8667609 | 0.80 | PSMB5 (0.43) | CCR1BACE1BACE2CTSD | |
| SCHEMBL6929977 | 0.80 | HPGDS (0.52) | CCR1MMEMMEL1BACE1CTRB1 | |
| Hydrochloric Acid SCHEMBL8897869 | 0.78 | CCR1 (0.43) | CCR1BACE1BACE2CTSD | |
| SCHEMBL8673190 | 0.76 | CYP3A4 (0.54) | CCR1CTRB1 | |
| SCHEMBL6924224 | 0.76 | NPC1 (0.49) | CCR1BACE1CTRB1BACE2CTSD | |
| SCHEMBL5699585 | 0.75 | PYGL (0.47) | BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763464-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-06-09 | — | — | US | disclosed |
| WO-1997019061-A1 | RETROVIRAL AGENTS CONTAINING ANTHRANILAMIDE, SUBSTITUTED BENZAMIDE AND OTHER SUBUNITS, AND METHODS OF USING SAME | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-05-29 | — | — | WO | disclosed |