Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 3/20 | 0.52 |
| ▸ | CCR1 | P32246 | 4/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927619 | 0.88 | CTRB1 (0.50) | HPGDSCCR1CTRB1MMEMMEL1 | |
| SCHEMBL6929416 | 0.85 | HPGDS (0.58) | HPGDSCCR1CTRB1BACE1KDM4E | |
| SCHEMBL6931268 | 0.85 | HPGDS (0.58) | HPGDSCCR1CTRB1BACE1KDM4E | |
| SCHEMBL6925409 | 0.85 | HPGDS (0.58) | HPGDSCCR1CTRB1BACE1KDM4E | |
| SCHEMBL14005615 | 0.82 | HPGDS (0.58) | HPGDSCTRB1MMEMMEL1BACE1 | |
| SCHEMBL8672247 | 0.80 | CCR1 (0.42) | HPGDSCCR1CTRB1MMEMMEL1 | |
| SCHEMBL8670883 | 0.76 | MAPK1 (0.44) | CCR1BACE1ALDH1A1 | |
| SCHEMBL3497782 | 0.76 | GPR132 (0.70) | HPGDSGPR132 | |
| SCHEMBL28592116 | 0.76 | GPR132 (0.70) | HPGDSGPR132 | |
| SCHEMBL8773564 | 0.75 | HPGDS (0.51) | HPGDSCTRB1MMEMMEL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801640-B1 | 2,5-DIAMINO-3,4-DISUBSTITUTED-1,6-DIPHENYLHEXANE ISOSTERES COMPRISING BENZAMIDE, SULFONAMIDE AND ANTHRANILAMIDE SUBUNITS AND METHODS OF USING SAME | USA (US) | 2003-03-26 | — | — | EP | claimed |