Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8672247 | 0.87 | CCR1 (0.42) | NPC1RAB9ACCR1BACE1 | |
| SCHEMBL8668860 | 0.77 | ATM (0.49) | BACE1 | |
| SCHEMBL6929977 | 0.76 | HPGDS (0.52) | ALDH1A1CCR1BACE1 | |
| SCHEMBL7382779 | 0.76 | ALDH1A1 (0.64) | MAPK1SMN1; SMN2ALDH1A1HPGDLMNA | |
| SCHEMBL8669429 | 0.76 | PSMB5 (0.44) | CCR1BACE1 | |
| Hydrochloric Acid SCHEMBL8897869 | 0.75 | CCR1 (0.43) | MAPK1SMN1; SMN2ALDH1A1CCR1CYP1A2 | |
| Hydrochloric Acid SCHEMBL8667609 | 0.75 | PSMB5 (0.43) | CCR1BACE1 | |
| SCHEMBL6927619 | 0.74 | CTRB1 (0.50) | NPC1RAB9ACCR1BACE1 | |
| SCHEMBL8673190 | 0.73 | CYP3A4 (0.54) | MAPK1ALDH1A1MEN1KMT2ACCR1 | |
| SCHEMBL5699585 | 0.72 | PYGL (0.47) | ALDH1A1HPGDLMNACYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763464-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-06-09 | — | — | US | disclosed |
| WO-1997019061-A1 | RETROVIRAL AGENTS CONTAINING ANTHRANILAMIDE, SUBSTITUTED BENZAMIDE AND OTHER SUBUNITS, AND METHODS OF USING SAME | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-05-29 | — | — | WO | disclosed |