Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.71 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.71 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.71 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.68 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.68 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.68 |
| ▸ | STK39 | Q9UEW8 | 10/20 | 0.65 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.64 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.64 |
| ▸ | FADS1 | O60427 | 2/20 | 0.64 |
| ▸ | PARG | Q86W56 | 2/20 | 0.60 |
| ▸ | PNLIP | P16233 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868077 | 0.88 | STK39 (0.77) | PTGS1TBXAS1MAPK1PTGS2MAPK14 | |
| Hydrochloric Acid SCHEMBL11777767 | 0.86 | STK39 (0.75) | PTGS1TBXAS1MAPK1PTGS2MAPK14 | |
| SCHEMBL11680848 | 0.84 | STK39 (0.71) | PTGS1TBXAS1MAPK1PTGS2MAPK14 | |
| SCHEMBL10359778 | 0.84 | HSPD1 (0.63) | P2RX1P2RX4P2RX7HSPD1HSPE1 | |
| 3,3',4',5-Tetrachlorosalicylanilide SCHEMBL29367227 | 0.83 | PTGS1 (1.00) | PTGS1TBXAS1MAPK1PTGS2MAPK14 | |
| 3,3',4',5-Tetrachlorosalicylanilide SCHEMBL168748 | 0.83 | PTGS1 (1.00) | PTGS1TBXAS1MAPK1PTGS2MAPK14 | |
| SCHEMBL29375129 | 0.83 | PTGS1 (0.77) | PTGS1TBXAS1MAPK1PTGS2MAPK14 | |
| SCHEMBL649911 | 0.83 | PTGS1 (0.77) | PTGS1TBXAS1MAPK1PTGS2MAPK14 | |
| SCHEMBL11932152 | 0.81 | P2RX1 (1.00) | P2RX1P2RX4P2RX7FADS1 | |
| SCHEMBL5631068 | 0.81 | P2RX1 (0.77) | P2RX1P2RX4P2RX7HSPD1HSPE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693919-B1 | ORAL COMPOSITIONS FOR TREATING PLAQUE AND GINGIVITIS CONTAINING A NONCATIONIC ANTIBACTERIAL AGENT AND A BICARBONATE SALT | PROCTER & GAMBLE (US) | 1998-12-23 | — | — | EP | disclosed |
| US-5290541-A | Methods for making oral compositions | THE PROCTER & GAMBLE COMPANY (US) | 1994-03-01 | — | — | US | disclosed |
| WO-1992010991-A1 | METHODS FOR MAKING ORAL COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |