Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668968 | 0.96 | SMN1; SMN2 (0.39) | ALDH1A1LMNACYP2C9HPGDDDAH1 | |
| SCHEMBL8443200 | 0.92 | KMT2A (0.42) | ALDH1A1LMNACYP2C9HPGDDDAH1 | |
| SCHEMBL8550349 | 0.85 | KDM4E (0.42) | ALDH1A1LMNAHPGDMAPTKMT2A | |
| SCHEMBL8669339 | 0.83 | MEN1 (0.39) | ALDH1A1LMNAKMT2ANPC1PKM | |
| SCHEMBL8670481 | 0.83 | ALDH1A1 (0.36) | ALDH1A1LMNACYP2C9HPGDDDAH1 | |
| SCHEMBL8672723 | 0.82 | MEN1 (0.38) | ALDH1A1LMNAHPGDMAPTKMT2A | |
| SCHEMBL8672637 | 0.78 | SMN1; SMN2 (0.37) | ALDH1A1LMNACYP2C9HPGDDDAH1 | |
| SCHEMBL8441860 | 0.78 | DRD2 (0.46) | ADRA1ADRD3KCNH2 | |
| SCHEMBL5134227 | 0.77 | MAPT (0.51) | ALDH1A1LMNACYP2C9HPGDDDAH1 | |
| SCHEMBL8551897 | 0.77 | LMNA (0.35) | LMNAMAPTKMT2ANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840910-A | Pyridine derivatives having anti-ulcerative activity | ESAI CO., LTD. (JP) | 1998-11-24 | — | — | US | disclosed |