Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 10/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.51 |
| ▸ | NOTCH1 | P46531 | 2/20 | 0.49 |
| ▸ | RBPJ | Q06330 | 2/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | CCKAR | P32238 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800985 | 0.83 | OXTR (0.54) | CCKBRKCNH2CCKAR | |
| SCHEMBL8667954 | 0.79 | CCKBR (0.48) | CCKBRKCNH2CCKAR | |
| SCHEMBL8674133 | 0.79 | CCKBR (0.48) | CCKBRKCNH2CCKAR | |
| SCHEMBL8940414 | 0.79 | FNTA (0.54) | CCKBRKCNH2CCKAR | |
| SCHEMBL7967402 | 0.79 | CCKBR (0.79) | CCKBRKCNH2SENP1NOTCH1RBPJ | |
| SCHEMBL8674526 | 0.79 | CCKBR (0.47) | CCKBRKCNH2SENP1CCKAR | |
| SCHEMBL8761230 | 0.77 | CCKBR (0.79) | CCKBRKCNH2SENP1NOTCH1RBPJ | |
| SCHEMBL8801329 | 0.77 | CCKBR (0.49) | CCKBRKCNH2PSEN1PSEN2APH1B | |
| SCHEMBL4415376 | 0.77 | CCKBR (0.61) | CCKBRKCNH2SENP1NOTCH1RBPJ | |
| SCHEMBL8420210 | 0.77 | KCNH2 (0.72) | CCKBRKCNH2SENP1CCKARSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843941-A | Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1998-12-01 | — | — | US | disclosed |