Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.53 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.41 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674285 | 0.81 | NISCH (0.45) | ACACBCYP1A2TRAP1AKR1C3ALDH1A1 | |
| SCHEMBL8675155 | 0.80 | DPP8 (0.41) | MTNR1AMTNR1BTIPARPHSP90B1TRAP1 | |
| SCHEMBL8673747 | 0.78 | NAMPT (0.45) | MTNR1AMTNR1BLIPEHDAC1ALDH1A1 | |
| SCHEMBL8677167 | 0.76 | ACACB (0.43) | ACACB | |
| SCHEMBL5458119 | 0.71 | MTNR1A (0.50) | MTNR1AMTNR1BABHD6HDAC1HDAC6 | |
| SCHEMBL16638014 | 0.70 | ABHD6 (0.61) | MTNR1AMTNR1BABHD6TIPARPHSP90B1 | |
| SCHEMBL14067231 | 0.70 | ABHD6 (0.61) | MTNR1AMTNR1BABHD6ACACBTIPARP | |
| SCHEMBL55491 | 0.69 | MTNR1A (1.00) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL1361406 | 0.68 | MTNR1A (0.65) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL1361403 | 0.68 | MTNR1A (0.65) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726197-A | ADRENORECEPTORS AND ADMINISTERING | SYNTEX (U.S.A.) INC. (US) | 1998-03-10 | — | — | US | disclosed |