Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | TRAP1 | Q12931 | 4/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674285 | 0.84 | NISCH (0.45) | TRAP1NAMPTL3MBTL1ALDH1A1 | |
| SCHEMBL8677167 | 0.82 | ACACB (0.43) | NAMPTDRD2 | |
| SCHEMBL8673747 | 0.81 | NAMPT (0.45) | NAMPTTMEM97SIGMAR1MTNR1AMTNR1B | |
| SCHEMBL8673285 | 0.80 | MTNR1A (0.53) | TRAP1TIPARPHSP90B1MTNR1AMTNR1B | |
| SCHEMBL10627455 | 0.74 | LIPE (0.45) | DPP8DPP9DPP7TRAP1NAMPT | |
| SCHEMBL11974929 | 0.72 | KCNH2 (0.41) | DPP8DPP9DPP7TRAP1TIPARP | |
| Hydrochloric Acid SCHEMBL1025747 | 0.70 | KCNH2 (0.40) | DPP8DPP9DPP7TRAP1TIPARP | |
| SCHEMBL8227303 | 0.69 | TRAP1 (0.55) | DPP8DPP9DPP7TRAP1NAMPT | |
| SCHEMBL21273227 | 0.68 | NAMPT (0.41) | DPP8DPP9DPP7TRAP1NAMPT | |
| SCHEMBL8673301 | 0.68 | ALDH1A1 (0.48) | TMEM97SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726197-A | ADRENORECEPTORS AND ADMINISTERING | SYNTEX (U.S.A.) INC. (US) | 1998-03-10 | — | — | US | disclosed |