Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 10/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675155 | 0.82 | DPP8 (0.41) | DRD2NAMPT | |
| SCHEMBL8674285 | 0.81 | NISCH (0.45) | ACACBKMT2ANAMPT | |
| SCHEMBL8673747 | 0.78 | NAMPT (0.45) | NAMPTNOTUM | |
| SCHEMBL8673285 | 0.76 | MTNR1A (0.53) | ACACB | |
| SCHEMBL31459216 | 0.70 | ABHD6 (0.44) | ACACBDRD2NAMPTNOTUMTEAD1 | |
| SCHEMBL7475070 | 0.68 | TYK2 (0.41) | ACACBDRD2MEN1KMT2ANAMPT | |
| SCHEMBL20178642 | 0.66 | NOTUM (0.43) | ACACBDRD2MEN1KMT2ANOTUM | |
| SCHEMBL8673301 | 0.65 | ALDH1A1 (0.48) | — | |
| SCHEMBL2930889 | 0.64 | PHGDH (0.50) | ACACBDRD2P2RX7MEN1KMT2A | |
| SCHEMBL27510912 | 0.63 | NISCH (0.34) | ACACBDRD2TEAD1TEAD4TEAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726197-A | ADRENORECEPTORS AND ADMINISTERING | SYNTEX (U.S.A.) INC. (US) | 1998-03-10 | — | — | US | disclosed |