Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668045 | 0.85 | POLB (0.46) | HTTLMNAPOLBHIF1ANPSR1 | |
| SCHEMBL17448265 | 0.83 | HTR6 (0.47) | HTR6HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL27905740 | 0.78 | CNR2 (0.41) | HPGDHTTSMN1; SMN2LMNAPOLB | |
| SCHEMBL8673748 | 0.77 | PTGS1 (0.60) | HTR6LMNAHIF1ANPSR1MAPT | |
| SCHEMBL5558582 | 0.76 | PTGS2 (0.47) | HPGDHTTSMN1; SMN2LMNAPOLB | |
| SCHEMBL27985045 | 0.75 | CHRM2 (0.50) | HTR6HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL27790010 | 0.75 | GAA (0.47) | HPGDHTTSMN1; SMN2LMNAPOLB | |
| SCHEMBL5799040 | 0.74 | PTGS2 (0.46) | HPGDHTTSMN1; SMN2LMNAPOLB | |
| SCHEMBL6025591 | 0.74 | PTGS2 (0.48) | HPGDHTTSMN1; SMN2LMNAHIF1A | |
| SCHEMBL5553721 | 0.74 | AKR1C3 (0.44) | HPGDHTTSMN1; SMN2LMNAESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750558-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1998-05-12 | — | — | US | disclosed |