Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27905740 | 0.80 | CNR2 (0.41) | GAAHTTMAPTKMT2AMEN1 | |
| SCHEMBL2005833 | 0.77 | PTGS2 (0.57) | GAAMAPTKMT2AMEN1LMNA | |
| SCHEMBL8673753 | 0.75 | HTR6 (0.43) | GAAHTTMAPTKMT2AMEN1 | |
| SCHEMBL2004074 | 0.73 | PTGS1 (0.58) | GAAMAPTKMT2AMEN1LMNA | |
| SCHEMBL6024850 | 0.73 | HTT (0.43) | GAAHTTMAPTKMT2AMEN1 | |
| SCHEMBL6025108 | 0.72 | CNR2 (0.47) | GAAHTTMAPTKMT2AMEN1 | |
| SCHEMBL6025591 | 0.71 | PTGS2 (0.48) | HTTMAPTKMT2AMEN1HPGD | |
| SCHEMBL5799040 | 0.71 | PTGS2 (0.46) | GAAHTTMAPTKMT2AMEN1 | |
| SCHEMBL5553721 | 0.71 | AKR1C3 (0.44) | HTTMAPTKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL6025282 | 0.70 | PTGS1 (0.47) | HTTMAPTKMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |